Triterpene glycosides from thalictri herba. II

Five new triterpene glycosides were isolated from the methanolic extract of Thalictri Herba (Takatogusa), the dried aerial parts of Thalictrum sp. plants (Ranunculaceae). They were designated as thalictosides III (1) and IV (2), being cycloartane-type glycosides, and thalictosides VI (3), VII (4) and VIII (5), being oleanene-type glycosides. By chemical and spectroscopic evidence, their structures were elucidated as 22R-21S,23R-epoxy- and 22R-21R,23R-epoxy-21-methoxycycloart-24-en-3 beta,22,30-triol 3-O-alpha-L-rhamnopyranosyl-(1-->2)-[alpha-L-rhamnopyranosyl-(1-->6)]- beta-D-glucopyranosides (1 and 2, respectively), 3-O-beta-D-glucopyranosyl-(1-->3)-alpha-L- rhamnopyranosyl-(1-->4)-beta-D-xylopyranosyl hederagenin 28-O-beta-D-glucopyranosyl ester (3) and 3-O-alpha-L-rhamnopyranosyl-(1-->3)-beta-D-glucopyranosyl-(1-->3)-alpha- L- rhamnopyranosyl-(1-->4)-beta-D-xylopyranosyl oleanolic acid and hederagenin 28-O-beta-D-glucopyranosyl esters (4 and 5, respectively).