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[Chronic osteomyelitis of mandibulae]
Nihon Rinsho. Japanese Journal of Clinical Medicine
|February 1, 1994
Summary
Acute osteomyelitis of the mandible, often stemming from dental infections, can lead to Vincent's Syndrome. Some oral streptococci strains form biofilms and resist antibiotics, complicating treatment and potentially requiring jaw amputation.
Area of Science:
- Oral and Maxillofacial Surgery
- Infectious Diseases
- Bacteriology
Context:
- Osteomyelitis of the mandible arises from bacterial infections, frequently linked to third molar pericoronitis or carious tooth infections.
- Acute osteomyelitis can progress to chronic, recalcitrant forms, posing significant treatment challenges.
Purpose:
- To highlight the clinical presentation and microbial characteristics of mandibular osteomyelitis.
- To discuss the progression from acute to chronic stages and associated treatment difficulties.
Summary:
- Mandibular osteomyelitis, often initiated by odontogenic infections, can manifest as Vincent's Syndrome (mental nerve palsy).
- Specific Oral Streptococci strains exhibit antibiotic resistance (penicillins, cephalosporins) and biofilm-forming capabilities, complicating management.
- Treatment failure may necessitate surgical interventions like debridement or decortication, with jaw amputation as a last resort.
Impact:
- Informs clinicians about the complex nature of mandibular osteomyelitis and the role of specific bacterial virulence factors.
- Emphasizes the need for effective antimicrobial strategies and timely surgical intervention to prevent severe outcomes.
- Underscores the potential for antibiotic resistance and biofilm formation in odontogenic infections leading to severe jaw pathology.