Sex hormones in the kidney and endolymphatic sac. An immunohistological study

Autopsy specimens of kidney and endolymphatic sac were studied in terms of progesterone (P), estradiol (E), testosterone (T), dihydrotestosterone (DHT) and aldosterone (A) using the peroxidase-antiperoxidase method. The results obtained were as follows: The epithelial cells of the renal tubules were positive to P, E, T, DHT and A. The epithelial cells of the endolymphatic sac were also positive to these sex hormones though varying in stainability among cases. In view of the immunohistological findings of sex hormones and aldosterone, the resorptive and regulative function of the epithelium in the kidney and endolymphatic sac is discussed.