[Granular cell tumor of the esophagus]

Granular cell tumor is a neoplasm usually benign, which only in two percent of the cases affects the esophagus. Histologically it is composed by two kind of cells: granular and angled body cells. The histogenesis of this tumor remains controversial; however, it has been recently demonstrated, by immunohistochemical methods, the presence of proteins that are specific of the nervous system. The diagnosis is frequently done incidentally and by endoscopic biopsy. We report a case of granular cell tumor of the distal esophagus found incidentally during a routine endoscopic examination. We review the English and Spanish literatures, focussing on the histological and diagnostic peculiarities. The clinical management and the different available therapeutics, according to symptoms and tumor size, are discussed.