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Updated: Aug 11, 2026

Peptide-based Identification of Functional Motifs and their Binding Partners
Published on: June 30, 2013
[Subclinical Crohn disease in acquired immunodeficiency syndrome]
D Moreno Sánchez1, J A Solís Herruzo, J Medina Asensio
1Hospital 12 de Octubre, Facultad de Medicina, Universidad Complutense, Madrid.
Abstract:
We report the case of a patient suffering from acquired immunodeficiency syndrome and hepatitis B and D virus-related cirrhosis of the liver who was diagnosed as subclinical Crohn's disease. We attribute this clinical course to abnormality of intestinal immune system induced by the human immunodeficiency virus. Concomitant hepatitis B and D virus infection may have contributed. This observation supports the hypothesis of helper-inducer T cells (CD4 T cells) having a critical role in the immunopathogenesis of Crohn's disease and its clinical expression.
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