Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Adenosine-induced torsades de pointes

G R Harrington1, E G Froelich

  • 1Critical Care Medicine Service, Walter Reed Army Medical Center, Washington, DC 20307.

Chest
|April 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Massive intraoperative pulmonary embolism coincident with the administration of succinylcholine.

Anesthesia and analgesia·1998
Same author

Intraabdominal fire during laparoscopic cholecystectomy.

Anesthesiology·1995
Same author

The effect of arterial lines on blood-drawing practices and costs in intensive care units.

Chest·1995
Same author

Multicenter trial of a new thoracic electrical bioimpedance device for cardiac output estimation.

Critical care medicine·1994
Same author

Non-operative management of gastric perforation secondary to cardiopulmonary resuscitation.

Intensive care medicine·1994
Same author

Noninvasive monitoring.

The American journal of medicine·1993

Adenosine is a useful diagnostic and therapeutic tool for cardiac arrhythmias due to its short half-life and safety. However, this case highlights a rare instance where adenosine can induce polymorphic ventricular tachycardia.

Area of Science:

  • Cardiology
  • Pharmacology

Background:

  • Adenosine is increasingly utilized for diagnosing and treating cardiac arrhythmias.
  • Its favorable pharmacokinetic profile, including a short half-life and minimal major complications, supports its use.

Observation:

  • This report details a specific case involving a patient experiencing an adverse reaction to adenosine.
  • The patient developed polymorphic ventricular tachycardia, a potentially serious heart rhythm disturbance.

Findings:

  • Adenosine administration, while generally safe, can paradoxically trigger specific arrhythmias.
  • Polymorphic ventricular tachycardia was observed as a direct consequence of adenosine therapy in this instance.

Implications:

  • Clinicians should be aware of the potential for adenosine to induce ventricular arrhythmias, even in the absence of pre-existing conditions.

Related Experiment Videos

  • This case underscores the importance of careful patient monitoring during adenosine administration for cardiac dysrhythmias.
  • Further investigation into the mechanisms underlying adenosine-induced polymorphic ventricular tachycardia may refine treatment protocols.