Early cold training in newborn rats and dynamics of brain biochemical maturation

The aim of the experiment was to investigate the influence of cold training in early postnatal life, on the dynamics of some biochemical brain parameters. Studies carried out on 96 Wistar newborn rats led to the following conclusions: chronic exposure to -12 degrees C, 10 min. daily, starting with day 1, or 7, 14, 21, and 30 days induces a significant stimulation of 32P-incorporation into brain phospholipids (in 14-, 21-, and 30-day-old rats), into phosphoproteins, cerebral DNA and RNA (especially in 14-day-old-rats.) The authors discuss the biological significance of these findings.