Recurrent Löfgren's syndrome in three patients with sarcoidosis

Löfgren's syndrome (acute onset of sarcoidosis with erythema nodosum, arthritis, sometimes fever and bilateral hilar lymphoma) is a well known clinical entity. Recurrent Löfgren's syndrome is, however, extremely rare. We report three cases of recurrent Löfgren's syndrome. The duration between the first manifestation of the syndrome and the first relapse varied between two and eight years. One of the patients had two relapses, two and six years after the initial onset of disease.