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Thrombotic thrombocytopenic purpura: MR demonstration of reversible brain abnormalities
P D'Aprile1, G Farchi, R Pagliarulo
1Neuroradiology Institute, Policlinico, University of Bari, Italy.
AJNR. American Journal of Neuroradiology
|January 1, 1994
Abstract:
We report a case of thrombotic thrombocytopenic purpura evaluated by MR. Multiple hyperintense foci on the T2-weighted images, observed principally in the brain stem and in the region of the basal nuclei, and neurologic signs disappeared after 15 days of therapy.
Insights
Thrombotic thrombocytopenic purpura (TTP) patients showed brain lesions on MRI scans. These TTP-related neurological signs and MRI findings resolved after treatment.
Area of Science:
- Neurology
- Radiology
- Hematology
Background:
- Thrombotic thrombocytopenic purpura (TTP) is a rare hematologic disorder.
- Neurological manifestations are common in TTP and can be severe.
- Magnetic Resonance (MR) imaging is a valuable tool for evaluating neurological involvement in TTP.