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Updated: Jul 30, 2026

An Experimental Paradigm for the Prediction of Post-Operative Pain (PPOP)
Published on: January 27, 2010
The frequency of postdural puncture headache in obstetric patients: a prospective study comparing the 24-gauge versus
D H Sears1, M I Leeman, L J Jassy
1Department of Anesthesiology, Mercy Hospital and Medical Center, San Diego, CA 92103.
Study Objective:
To compare the frequency of postdural puncture headache (PDPH) in obstetric patients when using the 24-gauge or the larger 22-gauge Sprotte needle.
Design:
Prospective, randomized study.
Setting:
Four hospitals.
Patients:
375 ASA physical status I and II cesarean section and postpartum tubal ligation patients.
Interventions:
Obstetric patients were randomly assigned to receive spinal anesthesia via a midline dural puncture using the 24-gauge or the 22-gauge Sprotte needle.
Measurements And Main Results:
The rate of PDPH was determined by a postoperative visit by the anesthesiologist as well as questioning patients by telephone 1 week or more after discharge. In the 24-gauge Sprotte needle group (n = 186), 2 mild and 1 moderate PDPHs were reported, for an overall rate of 1.61%. In the 22-gauge Sprotte needle group (n = 189), 2 mild and 1 moderate PDPHs were reported, for an overall rate of 1.59%. All headaches except 1 resolved within 72 hours with conservative treatment. One patient from the 22-gauge Sprotte needle group required an epidural blood patch. There were no failed blocks in either group.
Conclusions:
Our results suggest that the 22-gauge Sprotte needle, when compared with the smaller 24-gauge Sprotte needle, can be used in obstetric patients without increasing the frequency of PDPH.
