[Experimental epidural and conduction anesthesia with azacaine]

Experimental studies were undertaken to examine azacaine used in mice during conduction anesthesia and in rabbits during epidural anesthesia in 0.75, 2 and 0.75, 1% solutions, respectively. It was found that azacaine in the above doses is 1.5-3.5-fold superior to 2% solutions of lidocaine (xycaine) and trimecaine (mesocaine) in their effect duration. Histological studies of the rabbit spinal cord after epidural azacaine administration revealed no significant changes in brain tissues.