Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Laboratory tests for Lyme disease

B W Berger1

  • 1Department of Dermatology, State University of New York at Stony Brook.

Dermatologic Clinics
|January 1, 1994
PubMed
Summary
This summary is machine-generated.

Diagnosing Lyme disease is challenging due to unreliable laboratory tests lacking standardization. A positive Borrelia Burgdorferi culture is the only definitive laboratory confirmation for active Lyme disease.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The structure and function of platelet integrins.

Journal of thrombosis and haemostasis : JTH·2009
Same author

A first-tier rapid assay for the serodiagnosis of Borrelia burgdorferi infection.

Archives of internal medicine·2001
Same author

Infection with multiple strains of Borrelia burgdorferi sensu stricto in patients with Lyme disease.

Archives of dermatology·1999
Same author

Current aspects of Lyme disease and other Borrelia burgdorferi infections.

Dermatologic clinics·1997
Same author

Bloodstream invasion in early Lyme disease: results from a prospective, controlled, blinded study using the polymerase chain reaction.

The American journal of medicine·1995
Same author

Cultivation of Borrelia burgdorferi from human tick bite sites: a guide to the risk of infection.

Journal of the American Academy of Dermatology·1995
Same journal

The Evidence Is In: Devices and Biologics Reshaping Modern Dermatology.

Dermatologic clinics·2026
Same journal

Energy-Based Devices for Body Contouring.

Dermatologic clinics·2026
Same journal

Microfocused Ultrasound with Visualization for Skin Tightening: Clinical Applications, Safety, and Technical Considerations.

Dermatologic clinics·2026
Same journal

Devices in Onychomycosis: A Status Update.

Dermatologic clinics·2026
Same journal

Acne Laser Devices in Dermatology.

Dermatologic clinics·2026
Same journal

Fractional Laser Therapy for Androgenetic Alopecia: Mechanisms, Clinical Evidence, and Practical Implementation.

Dermatologic clinics·2026
See all related articles

Area of Science:

  • Medical Microbiology
  • Infectious Diseases
  • Clinical Diagnostics

Background:

  • Laboratory diagnosis of Lyme disease presents significant challenges.
  • Current diagnostic methods often lack sufficient sensitivity and specificity.
  • Interlaboratory standardization of Lyme disease testing remains insufficient.

Purpose of the Study:

  • To highlight the limitations in current laboratory diagnostic methods for Lyme disease.
  • To emphasize the need for improved diagnostic accuracy and standardization.

Main Methods:

  • Review of existing laboratory diagnostic approaches for Lyme disease.
  • Analysis of sensitivity, specificity, and standardization issues in current tests.

Main Results:

Related Experiment Videos

  • Existing laboratory tests for Lyme disease are often unreliable.
  • Lack of standardization across laboratories further complicates accurate diagnosis.
  • A positive culture for Borrelia Burgdorferi is the sole definitive laboratory finding.

Conclusions:

  • Current laboratory tests for Lyme disease require significant improvement.
  • Interlaboratory standardization is crucial for reliable Lyme disease diagnosis.
  • Clinical findings remain paramount, supported by laboratory results, with culture as the exception.