Evaluation of serum lactate dehydrogenase activity for estimation of energy expenditure in human subjects

We investigated the relationship between serum lactate dehydrogenase (LDH) activity and energy expenditure in young adults, evaluating their serum LDH activities in order to develop an index of energy expenditure. The results obtained were as follows. (1) There were significant correlations between the serum LDH activity and energy expenditure/day, energy expenditure/body weight/day and daily activity index in men. (2) There were significant correlations between the serum LDH activity and energy expenditure/day and daily activity index in women. (3) A group of men who 'rarely' exercised had lower levels of serum LDH activity than those who exercised 'sometimes' or 'usually', but little difference was noted between similar groups of women.