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[Malignant cerebral tumors in children]
1Institut Curie, service d'oncologie pédiatrique, Paris.
La Revue Du Praticien
|November 1, 1993
Summary
Malignant brain tumors are the leading cause of solid tumors in children, often presenting with intracranial hypertension. Advances in neurosurgery, radiotherapy, and chemotherapy improve outcomes while minimizing long-term side effects.
Area of Science:
- Pediatric Oncology
- Neuro-oncology
Context:
- Malignant brain tumors are the primary cause of solid tumors in children.
- They represent a significant cause of cancer-related mortality in pediatrics.
- Intracranial hypertension is the most common presentation of these tumors.
Purpose:
- To review recent therapeutic advances in pediatric brain tumors.
- To emphasize the importance of multidisciplinary care and clinical trials.
- To highlight the need for reduced toxicity in treatment to mitigate long-term sequelae.
Summary:
- Pediatric malignant brain tumors, including medulloblastoma, glioma, and ependymoma, require prompt diagnosis via emergency neuroradiological exploration due to signs like intracranial hypertension.
- Significant progress in neurosurgery, radiotherapy, and chemotherapy has been achieved in the past decade.
- Current treatment strategies prioritize effectiveness alongside reduced toxicity to prevent long-term central nervous system damage in children.
Impact:
- Improved survival rates for children with malignant brain tumors.
- Reduced incidence of long-term neurodevelopmental deficits in pediatric cancer survivors.
- Enhanced understanding and implementation of multidisciplinary care protocols for pediatric neuro-oncology.