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Updated: Aug 14, 2026

A Model to Simulate Clinically Relevant Hypoxia in Humans
Published on: December 22, 2016
[Effects of hyperoxia and hypoxia on cerebral circulation and intracranial pressure]
1Shanghai Institute of Physiology, Chinese Academy of Sciences.
Abstract:
Oxygen is an active stimulus of cerebral blood vessels. Hyperoxia can induce decrease in cerebral blood flow and intracranial pressure, but hypoxia increases cerebral blood flow and intracranial pressure. Both hyperoxia and hypoxia play an opposite role in cerebral circulation and intracranial pressure. Recent studies of cerebral circulation and intracranial pressure under hyperoxia and hypoxia were reviewed in the present paper with special reference to the correlation between cerebral circulation and intracranial pressure.
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