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[Results of planned immunization of Rh-negative subjects with Rh-positive blood]
Fifty-four men were immunized with Rh-positive blood for induction of anti-Rh antibodies. The method of immunization used allowed the planned effect to be obtained in 56% of cases. Starting with the 5th month after administration of the first antigenic stimulus the plasma of 17 subjects could be used for production of anti-D immunoglobulin. No reliable results were obtained in investigations of early phase of serologically undetectable immune response using the test of local haemolysis in gel (plaque-forming cells).
Fifty-four men were immunized with Rh-positive blood for induction of anti-Rh antibodies. The method of immunization used allowed the planned effect to be obtained in 56% of cases. Starting with the 5th month after administration of the first antigenic stimulus the plasma of 17 subjects could be used for production of anti-D immunoglobulin. No reliable results were obtained in investigations of early phase of serologically undetectable immune response using the test of local haemolysis in gel (plaque-forming cells).