[Fatal myocardial infarction in a young patient due to coronary arteritis]
D Favarato1, A J Mansur, L A Benvenuti
1Instituto do Coração do Hospital das Clínicas-FMUSP, São Paulo, SP.
Insights
A young man experienced myocardial infarction due to left anterior descending artery obstruction. Despite unsuccessful angioplasty, his fatal second heart attack was caused by rare giant cell coronary arteritis.
Area of Science:
- Cardiology
- Pathology
Background:
- A 34-year-old male presented with a history of acute anterior wall myocardial infarction at age 32.
- Subsequent stress testing and thallium myocardial scintigraphy confirmed myocardial ischemia.
Abstract:
A 34 year-old male patient suffered an acute anterior wall infarction at age 32. Myocardial ischemia was demonstrated later by stress testing and thallium myocardial scintigraphy. Coronary arteriography revealed a proximal 90% obstruction of the left anterior descending artery. The patient was submitted to percutaneous transluminal coronary angioplasty. The procedure was unsuccessful as the catheter could not progress through the obstruction. On follow-up, there was less than ideal adherence to medical treatment and the patient complained of occasional atypical non-effort related chest pain. Two years later the patient suffered a large fatal myocardial infarction. Necropsy disclosed that the cause of myocardial infarction was severe coronary arteritis of left circumflex artery with giant cell granulomas.
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