Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Early surgery for ruptured vertebrobasilar aneurysms

S J Peerless1, J A Hernesniemi, F B Gutman

  • 1Department of Neurological Surgery, University of Miami, Florida.

Journal of Neurosurgery
|April 1, 1994
PubMed
Summary

Early surgery for vertebrobasilar aneurysms is recommended for select patients. Good outcomes are achievable regardless of surgical timing for patients with good preoperative grades.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Molecular imaging for cancer immunotherapy.

Immuno-oncology technology·2022
Same author

Transforming the Perioperative Treatment Paradigm in Non-Metastatic RCC-A Possible Path Forward.

Kidney cancer (Clifton, Va.)·2018
Same author

Precision, complexity and stigma in advanced prostate cancer terminology: it is time to move away from 'castration-resistant' prostate cancer.

Annals of oncology : official journal of the European Society for Medical Oncology·2017
Same author

Correlation of B7-H3 with androgen receptor, immune pathways and poor outcome in prostate cancer: an expression-based analysis.

Prostate cancer and prostatic diseases·2016
Same author

Management of patients with advanced prostate cancer: recommendations of the St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) 2015.

Annals of oncology : official journal of the European Society for Medical Oncology·2016
Same author

Paucity of PD-L1 expression in prostate cancer: innate and adaptive immune resistance.

Prostate cancer and prostatic diseases·2015

Area of Science:

  • Neurosurgery
  • Vascular Neurology

Background:

  • Vertebrobasilar circulation aneurysms pose significant risks.
  • Surgical timing after subarachnoid hemorrhage (SAH) is a critical consideration.

Purpose of the Study:

  • To evaluate the outcomes of early versus delayed surgical intervention for vertebrobasilar aneurysms.
  • To determine the safety and efficacy of surgical timing in relation to SAH.

Main Methods:

  • Retrospective analysis of 1767 patients with vertebrobasilar aneurysms.
  • Comparison of surgical outcomes for patients operated on within 7 days versus more than 14 days post-SAH.
  • Assessment of patient outcomes based on Botterell grading.

Main Results:

  • Good or excellent outcomes were achieved in 80% of good-grade (1 or 2) patients within the first month, irrespective of surgical timing.

Related Experiment Videos

  • Overall operative mortality rates were similar for early (within 7 days) and delayed surgery.
  • Delayed ischemic neurological deficits occurred in 13% of patients due to vasospasm.

    • Conclusions:

    • Early surgery is recommended for good-grade patients with uncomplicated aneurysms and for those with recurrent hemorrhage risk.
    • Surgical timing does not significantly impact mortality or outcomes for good-grade patients.
    • Patient selection and preoperative grade are crucial factors in determining surgical outcomes for vertebrobasilar aneurysms.