Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Diarrhea associated with antibiotic therapy]

D Buda1, G L Guarnieri

  • 1Divisione di Medicina Generale, Ospedale Civile S. Maria dei Battuti, Conegliano Veneto, Treviso.

Minerva Medica
|January 1, 1994
PubMed
Summary

Preventing antibiotic-associated diarrhea (AAD) is crucial due to high costs. This study assessed 24 cases, finding Clostridium difficile in 50%, and proposes rational antibiotic use, patient isolation, and improved sanitation to mitigate AAD.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Herpes simplex virus type 1 suppresses the transformed phenotype of cultured cells.

Acta virologica·2019
Same author

Evaluation of heart rate recovery in relation to playing position in professional soccer players.

The Journal of sports medicine and physical fitness·2012
Same author

Albumin excretion in diabetic patients in the setting of acute myocardial infarction: association with 3-year mortality.

Diabetologia·2004
Same author

[Physical treatment of deep venous thrombosis: bed rest or mobilization?].

Minerva cardioangiologica·2001
Same author

[Compression therapy in deep venous thrombosis].

Minerva cardioangiologica·2001
Same author

Postphlebitic syndrome: clinical activity and tolerability of desmin, new LMW dermatan sulfate.

Angiology·1996

Area of Science:

  • Infectious Diseases
  • Gastroenterology
  • Hospital Epidemiology

Background:

  • Antibiotic-associated diarrhea (AAD) poses significant healthcare costs.
  • Clostridium difficile infection is a major cause of AAD.
  • Effective prevention strategies are needed to reduce AAD incidence and associated expenses.

Observation:

  • Twenty-four cases of diarrhea occurring during or after antibiotic therapy were evaluated.
  • Half of the cases (12/24) tested positive for Clostridium difficile.
  • No cases of pseudomembranous colitis were identified in the study cohort.

Findings:

  • Hospitalized patients exposed to Clostridium difficile-positive individuals contracted the illness despite precautions.
  • Vancomycin (1-2 g/day orally) proved effective for severe AAD cases (>10 stools/day).

Related Experiment Videos

  • Mild AAD cases ( <6 stools/day) caused by Clostridium difficile showed recovery without specific antibiotic treatment.

    • Implications:

    • Implementing rational antibiotic prescribing is essential for AAD prevention.
    • Patient isolation and stringent sanitary measures for dejections are recommended to control AAD spread.
    • These strategies can help reduce the economic burden associated with AAD and Clostridium difficile infections.