Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Tendon grafting with glutaraldehyde fixed material

W C McMaster, J Kouzelos, S Liddle

    Journal of Biomedical Materials Research
    |March 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The role of preoperative aspartate aminotransferase-to-platelet ratio index in predicting complications following total hip arthroplasty.

    BMC musculoskeletal disorders·2023
    Same author

    Painful Shoulder in Swimmers: A Diagnostic Challenge.

    The Physician and sportsmedicine·2016
    Same author

    Compression arthrodesis of the ankle following failed ankle arthroplasty using hoffmann® external fixation.

    Orthopedics·2014
    Same author

    Comparing the performance of six human papillomavirus tests in a screening population.

    British journal of cancer·2013
    Same author

    Heterotopic pancreatic tissue in the region of the pyloric orifice; a radiological and pathological analysis of five cases of clinically suspected peptic ulcer in which only pancreatic rests were found.

    Gastroenterology·2010
    Same author

    The Blood Sedimentation Test; Its History, Technique, Nature and Clinical Application.

    Canadian Medical Association journal·2010
    Same journal

    Optimizing the tensile properties of polyvinyl alcohol hydrogel for the construction of a bioprosthetic heart valve stent.

    Journal of biomedical materials research·2002
    Same journal

    Wear of conventional and cross-linked ultra-high-molecular-weight polyethylene acetabular cups against polished and roughened CoCr femoral heads in a biaxial hip simulator.

    Journal of biomedical materials research·2002
    Same journal

    Immobilization of natural macromolecules on poly-L-lactic acid membrane surface in order to improve its cytocompatibility.

    Journal of biomedical materials research·2002
    Same journal

    Light scattering and in vitro biocompatibility studies of poly (vinyl pyrrolidone) derivatives with amino-acid-dependent groups.

    Journal of biomedical materials research·2002
    Same journal

    Immobilization of an oxalate-degrading enzyme on silicone elastomer.

    Journal of biomedical materials research·2002
    Same journal

    An evaluation of the cytotoxic effects of orthodontic bonding adhesives upon a primary human oral gingival fibroblast culture and a permanent, human oral cancer-cell line.

    Journal of biomedical materials research·2002
    See all related articles

    Glutaraldehyde-fixed tendon shows promise as a biocompatible tendon prosthesis. This biomaterial integrates with host tissues and offers comparable strength to natural grafts, indicating potential for tendon replacement.

    Area of Science:

    • Biomaterials Science
    • Orthopedic Surgery
    • Tissue Engineering

    Background:

    • Tendon injuries require effective replacement strategies.
    • Biomaterials offer potential alternatives to autografts.
    • Glutaraldehyde fixation is a method to preserve biological tissues.

    Purpose of the Study:

    • To evaluate 0.2% buffered glutaraldehyde-fixed tendon as a potential tendon replacement prosthesis.
    • To assess the biocompatibility, function, and strength of the fixed tendon graft in vivo.
    • To compare the mechanical properties of the fixed tendon graft with fresh autogenous grafts.

    Main Methods:

    • In vivo implantation of glutaraldehyde-fixed tendon grafts in rabbit and chicken models.
    • Evaluation of graft compatibility, function, and strength.

    Related Experiment Videos

  • Tensile strength testing of fixed grafts against fresh autogenous controls.

    • Main Results:

    • The fixed tendon graft elicited no cellular rejection response.
    • The graft was successfully invaded and replaced by host tissues.
    • Anastomosis strength in tension compared favorably to fresh autogenous controls.

    Conclusions:

    • 0.2% buffered glutaraldehyde-fixed tendon demonstrates excellent biocompatibility.
    • The fixed tendon shows potential for successful integration and functional recovery.
    • This biomaterial presents a viable option for tendon prostheses.