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A Platform of Anti-biofilm Assays Suited to the Exploration of Natural Compound Libraries
Published on: December 27, 2016
[The antibacterial action of new hydrazide derivatives]
C Ciugureanu1, M Ungureanu, G Grosu
1Faculté de Chemie, Université Al. I. Cuza Iassy.
Abstract:
New derivatives of 4-aminobenzoic and 4-chlorine-2-hydroxybenzoic acids hydrazides were synthesized by the condensation reaction of these hydrazides with aldehydes and ketones, derivatives containing in their molecule azometine and hydrazone groups. The obtained products are potentially bioactive. The study of their "in vitro" biological activity was performed on some pathogenic germs, both gram-positive and gram-negative. The results show that the tested substances are more active towards the gram-positive germs.
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