Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Total parenteral nutrition

C R Fleming, D B McGill, H N Hoffman

    Mayo Clinic Proceedings
    |March 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Total parenteral nutrition (TPN) provides essential nutrients intravenously when oral intake is impossible. This innovative therapy offers significant benefits for patients with various gastrointestinal conditions, including home-based care.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Disparities in survival after trimodality therapy for esophageal adenocarcinoma.

    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus·2018
    Same author

    Hydroconductive and silver-impregnated foam dressings: a comparison.

    Journal of wound care·2017
    Same author

    Prognostic significance of lymph node yield in ypN0 rectal cancer.

    The British journal of surgery·2016
    Same author

    The Medical Bookshelf.

    Postgraduate medicine·2016
    Same author

    The hospital and education.

    Hospitals·2014
    Same author

    Studies on the Relationship of Treponemal Antibody to Probable Biologic False Positive Serologic Test for Syphilis.

    Transactions of the American Clinical and Climatological Association·2011
    Same journal

    Thyroid Dysfunction and the Risk of Clinically Relevant Depression: A Longitudinal Cohort Study.

    Mayo Clinic proceedings·2026
    Same journal

    37-Year-Old Woman With Jaundice.

    Mayo Clinic proceedings·2026
    Same journal

    34-Year-Old Woman With An Unidentified Overdose.

    Mayo Clinic proceedings·2026
    Same journal

    Use of Bronchoscopic Cryobiopsy in Evaluating Interstitial Lung Disease: Radiologic Predictors of Diagnostic Yield and Safety.

    Mayo Clinic proceedings·2026
    Same journal

    Advancing Pulmonary Fibrosis Care: Integrating Genomic Insights Into Clinical Practice.

    Mayo Clinic proceedings·2026
    Same journal

    RAAS Inhibition in the ICU: Stop, Continue, or Restart?

    Mayo Clinic proceedings·2026
    See all related articles

    Area of Science:

    • Clinical Nutrition
    • Gastroenterology
    • Intensive Care Medicine

    Background:

    • Total parenteral nutrition (TPN) is a critical medical intervention for patients unable to receive adequate nutrition orally or via tube feeding.
    • It involves intravenous administration of concentrated nutrients, including dextrose, amino acids, electrolytes, and vitamins, through a central venous catheter.
    • TPN bypasses the gastrointestinal tract, making it suitable for complex medical conditions.

    Observation:

    • Indications for TPN are diverse, encompassing intestinal fistulas, short bowel syndrome, pancreatitis, inflammatory bowel disease, and post-operative recovery.
    • It is also utilized in cases of infant diarrhea and hypermetabolic states.
    • The delivery method requires careful management to ensure nutrient delivery within normal fluid volumes.

    Related Experiment Videos

    Findings:

    • TPN solutions are formulated with synthetic amino acids or protein hydrolysates, macroelements, electrolytes, and vitamins.
    • Catheter insertion into a large central vein is necessary for administering hypertonic dextrose calories.
    • Successful implementation requires monitoring for potential complications.

    Implications:

    • Complications associated with TPN include catheter-related mechanical issues, infections, and metabolic disturbances.
    • Despite potential risks, TPN has demonstrated encouraging results in managing malnutrition.
    • The therapy has been successfully adapted for home-based care, reducing hospitalizations for select patients.