[Effect of viral hepatitis on the remission of macroglobulinemia]

A case of Waldenström's disease, whose IGM pathological clone was clearly diminished in concomitance with a hepatitis virus is reported. Remission lasted about a year after which the disease took up again with its typical biohumoral features. In view of other reported cases, various factors (chance, interferone, lymphocytotoxic action of the virus) capable of explaining such behaviour are hypothesized. It is concluded that the virus performed a temporary lymphocytotoxic action.