Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Infrared laser and bone metabolism: a pilot study

M Gordjestani1, L Dermaut, H Thierens

  • 1Department of Orthodontics, University of Ghent, Belgium.

International Journal of Oral and Maxillofacial Surgery
|February 1, 1994
PubMed
Summary

Infrared laser radiation did not affect bone healing in rat parietal bone defects. Technetium-99m methylene diphosphonate scintigraphy showed no difference in bone metabolic activity between treated and control groups after 28 days.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Radiation Sensitivity of Human CD34(+) Cells Versus Peripheral Blood T Lymphocytes of Newborns and Adults: DNA Repair and Mutagenic Effects.

Radiation research·2016
Same author

γ-H2AX foci as in vivo effect biomarker in children emphasize the importance to minimize x-ray doses in paediatric CT imaging.

European radiology·2014
Same author

The REQUITE project: validating predictive models and biomarkers of radiotherapy toxicity to reduce side-effects and improve quality of life in cancer survivors.

Clinical oncology (Royal College of Radiologists (Great Britain))·2014
Same author

Realising the European network of biodosimetry: RENEB-status quo.

Radiation protection dosimetry·2014
Same author

The first gamma-H2AX biodosimetry intercomparison exercise of the developing European biodosimetry network RENEB.

Radiation protection dosimetry·2014
Same author

Validation of semi-automatic scoring of dicentric chromosomes after simulation of three different irradiation scenarios.

Health physics·2014

Area of Science:

  • Biomedical Engineering
  • Surgical Innovation
  • Bone Regeneration Research

Background:

  • Surgical defects in bone require effective treatments for optimal healing.
  • Low-level laser therapy (LLLT) is explored for its potential to enhance tissue repair.
  • Understanding LLLT's effect on bone metabolism is crucial for clinical applications.

Purpose of the Study:

  • To investigate the impact of infrared laser radiation on bone metabolism in a rat model.
  • To evaluate the efficacy of laser therapy in promoting bone defect healing.

Main Methods:

  • Created circular parietal bone defects in six Wislander rats.
  • Divided rats into experimental (infrared laser) and control (sham irradiation) groups.
  • Assessed bone metabolism using technetium-99m methylene diphosphonate scintigraphy after 28 days.

Related Experiment Videos

Main Results:

  • No significant differences in bone metabolic activity were observed.
  • Laser treatment did not show a measurable effect on bone healing compared to controls.
  • Scintigraphy results indicated similar metabolic profiles in both groups.

Conclusions:

  • Infrared laser radiation, under the tested conditions, does not appear to enhance bone metabolism or healing in parietal bone defects.
  • Further research with varying laser parameters or models may be needed to explore LLLT's role in bone regeneration.