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Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
Published on: March 6, 2019
Are infants with bronchopulmonary dysplasia at risk for sudden infant death syndrome?
1Department of Neonatology, Mater Mothers' Hospital, South Brisbane, Queensland, Australia.
Insights
Preterm infants with bronchopulmonary dysplasia (BPD) are not at higher risk for sudden infant death syndrome (SIDS) or apparent life-threatening events (ALTE). Close monitoring and home oxygen support may mitigate risks in these vulnerable infants.
Area of Science:
- Neonatology
- Pediatric Pulmonology
- Perinatal Medicine
Background:
- Bronchopulmonary dysplasia (BPD) is a chronic lung disease in preterm infants.
- Changing patterns of chronic lung disease necessitate re-evaluation of risks.
- Sudden infant death syndrome (SIDS) and apparent life-threatening events (ALTE) are critical concerns in preterm infants.
Purpose of the Study:
- To compare SIDS and ALTE incidence in infants with BPD versus matched controls.
- To assess risks in the context of evolving chronic lung disease management.
- To evaluate the impact of current management strategies on SIDS/ALTE risk.
Main Methods:
- Study included 78 preterm infants (26-33 weeks gestation) with BPD and 78 birth weight-matched controls.
- Infants requiring home oxygen were identified.
- ALTE occurrence was assessed via parent interviews at a minimum of 8 months follow-up.
Main Results:
- No deaths occurred during follow-up.
- ALTE incidence was similar between the BPD group (8.9%) and control group (10.5%).
- No infants discharged on home oxygen experienced an ALTE.
Conclusions:
- Preterm infants with BPD do not appear to have an increased risk of SIDS compared to controls.
- Close oxygen monitoring and home oxygen therapy may reduce unrecognized hypoxemia.
- Routine home monitoring for all BPD infants may not be necessary.
Objective:
To compare the incidence of sudden infant death syndrome (SIDS) and apparent life-threatening event (ALTE) in infants with bronchopulmonary dysplasia (BPD) and birth weight-matched control infants in view of the changing pattern of chronic lung disease of prematurity.
Methods:
The study population consisted of 78 preterm infants of 26 to 33 weeks gestation who were diagnosed as having BPD and discharged. The 78 control infants were matched with the study infants for birth weight categories. Infants unable to maintain adequate oxygenation without supplemental oxygen when they were feeding well and thriving were discharged on home oxygen. All infants were at least 8 months of age at follow-up and information concerning the occurrence of any ALTE was obtained by direct parent interview.
Results:
No infant died during the period of follow-up. Seven (8.9%) of the study group compared with eight (10.5%) of the control infants had an ALTE. Three infants (one study, two control infants) were hospitalized for further investigation. No infant discharged on the home oxygen program had an ALTE.
Conclusions:
The data from this study suggest that preterm infants with BPD are not at increased risk from SIDS compared with preterm infants without this condition. This may be related to close monitoring of the infants' oxygenation status and the provision of home oxygen when appropriate, which should eliminate episodes of unrecognized and untreated hypoxemia. Home monitoring for infants with BPD may not be warranted.
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