P 100 latency of the visual evoked response in multiple sclerosis compared with normative data

P 100 latency of the pattern-reversal visual evoked response in 65 patients with definite multiple sclerosis was compared with normative data derived from 65 control subjects. On the basis of the results of distribution analyses it could be concluded that in definite multiple sclerosis there is visual system involvement in all patients, even if their P 100 latencies are within normal limits. Implications with respect to suspected multiple sclerosis were discussed.