Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Visual evoked potentials in multiple sclerosis: frequency response shows reduced alpha amplitude

C Basar-Eroglu1, K Warecka, M Schürmann

  • 1Institute of Psychology and Cognition Research, University of Bremen, Germany.

The International Journal of Neuroscience
|December 1, 1993
PubMed
Summary

Multiple sclerosis (MS) patients show altered visual evoked potentials (VEPs). Alpha frequency components of VEPs were significantly reduced, suggesting a link to primary sensory processing deficits in MS.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Oscillatory Activities in Multiple Frequency Bands in Patients with Schizophrenia During Motion Perception.

Clinical EEG and neuroscience·2022
Same author

Evaluation of cochlear implant electrode scalar position by 3 Tesla magnet resonance imaging.

Scientific reports·2021
Same author

Standardized microgel beads as elastic cell mechanical probes.

Journal of materials chemistry. B·2020
Same author

[Perspectives of genome editing in otorhinolaryngology].

HNO·2019
Same author

Shade Stability of Polymer Infiltrated and Resin Nano Ceramic Crowns after Dynamic Chewing Simulation.

The European journal of prosthodontics and restorative dentistry·2018
Same author

Investigation of SiO<sub>2</sub>-Al<sub>2</sub>O<sub>3</sub> nanolaminates for protection of silver reflectors.

Applied optics·2017

Area of Science:

  • Neuroscience
  • Clinical Neurology

Background:

  • Multiple sclerosis (MS) is a demyelinating disease affecting the central nervous system.
  • MS often involves optic nerve damage, leading to visual pathway dysfunction.

Purpose of the Study:

  • To investigate alterations in visual evoked potentials (VEPs) in multiple sclerosis patients.
  • To analyze the frequency-specific components of VEPs to understand sensory processing in MS.

Main Methods:

  • Measured VEPs in 16 MS patients and 20 healthy controls.
  • Performed frequency domain analysis on VEPs to examine different frequency components.
  • Analyzed latencies and amplitudes of VEP peaks.

Main Results:

  • MS patients exhibited prolonged VEP latencies and reduced amplitudes compared to controls.

Related Experiment Videos

  • Frequency analysis revealed a marked reduction in alpha (7-12 Hz) VEP components.
  • Theta (4-7 Hz) VEP components remained unaltered in MS patients.

    • Conclusions:

    • The frequency-dependent VEP alterations suggest distinct roles for different frequency components in sensory processing.
    • Reduced alpha responses in MS patients indicate a link to impaired primary sensory processing.
    • Unaffected theta responses suggest they may reflect associative sensory processing, less dependent on direct sensory input.