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[The therapeutic posture in desmoid tumor]
A Moral Duarte1, J Piulachs Clapera, E M Targarona Soler
1Departamento de Cirugía, Hospital Clínic i Provincial de Barcelona, Universidad de Barcelona.
Medicina Clinica
|February 26, 1994
Summary
Radical surgery is the recommended treatment for desmoid tumors, including recurrences. Medical therapies like tamoxifen and sulindac may be used in specific cases for this locally aggressive neoplasm.
Area of Science:
- Oncology
- Surgical Pathology
Context:
- Desmoid tumors are benign neoplasms with high local recurrence rates.
- Their aggressive nature often necessitates radical surgical intervention, particularly for extra-abdominal presentations.
Purpose:
- To evaluate treatment outcomes for desmoid tumors.
- To assess the efficacy of surgical and medical interventions over time.
Summary:
- Twelve patients with desmoid tumors underwent evaluation of treatments received between 1983 and 1993.
- Surgical treatment was primary, with 27 interventions performed. Adjuvant therapies included tamoxifen, sulindac, and radiotherapy in select cases.
- Mean follow-up was 38 months; no mortality occurred, but 5 patients remained without disease-free status.
Impact:
- Highlights the critical role of radical surgery in managing desmoid tumors.
- Suggests a tailored approach combining surgery with medical treatment for specific patient profiles.
- Informs clinical decision-making for optimizing desmoid tumor management and improving patient outcomes.