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[Gonococcal septicemia. 1 case]

M Chousterman, F Gretillat, J P Petite

    La Nouvelle Presse Medicale
    |February 28, 1976
    PubMed
    Summary
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    Disseminated gonococcal infection (DGI) is rare, but this case highlights its presentation with polyarthritis and skin lesions. Prompt diagnosis and a 45-day course of intravenous penicillin G and gentamicin led to a successful clinical and bacteriological recovery.

    Area of Science:

    • Infectious Diseases
    • Microbiology
    • Clinical Medicine

    Background:

    • Disseminated gonococcal infection (DGI) is a rare systemic complication of Neisseria gonorrhoeae.
    • This case report focuses on the clinical presentation and management of DGI in France, a region with limited reported cases.

    Observation:

    • A 41-year-old woman presented with acute polyarthritis and characteristic skin lesions, suggestive of DGI.
    • Elevated liver enzymes and jaundice complicated the diagnosis due to pre-existing alcoholic cirrhosis.
    • A systolic murmur raised suspicion for endocarditis, a potential complication of DGI.

    Findings:

    • Neisseria gonorrhoeae was identified in blood cultures and cutaneous bullae scrapings.
    • The patient received a 45-day treatment regimen of intravenous penicillin G sodium and intramuscular gentamicin.

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  • Complete clinical and bacteriological resolution was achieved following the prescribed therapy.

    • Implications:

    • This case underscores the importance of considering DGI in patients with polyarthritis and skin manifestations, even in low-prevalence areas.
    • Effective treatment strategies involving prolonged antibiotic courses are crucial for managing DGI.
    • Early diagnosis and appropriate management can lead to favorable outcomes, preventing severe complications.