[A comparative trial of hemodynamics and pulmonary function in patients with chronic lung disease complicated with or...

In order to determine the hemodynamics and pulmonary function during exercise, 20 patients with chronic lung disease complicated with (group A) or without (group B) pulmonary hypertension were studied. FEV1% in group A was lower than that in group B at rest, the increase in VE, VO2, O2-pulse in patients with pulmonary hypertension were lower than in patients without it during exercise. We speculated that exercise ability in patients with chronic lung disease may be effected by not only ventilation but also increased pulmonary arterial pressure.