[Fluidity of red blood cell membrane from mouse infected with Malaria parasite]

The fluidity of membrane lipid regions of Plasmodium berghei- or Plasmodium yoelii-infected red blood cells has been determined by the fluorescence polarization technique using 1,6-diphenyl-1,3,5-hexatriene (DPH) as a probe. The results showed that the fluidity of Plasmodium (berghei or yoelii)-infected red blood cell membranes was increased significantly as compared with that of normal controls judging from the degree of polarization and the microviscosity. Its mechanism was discussed briefly.