Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Regional pulmonary function test--pulmonary nuclear medicine]

O Kitada1

  • 15th Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya.

Rinsho Byori. the Japanese Journal of Clinical Pathology
|April 1, 1994
PubMed
Summary

Pulmonary nuclear medicine uses three main methods for ventilation studies: xenon-133 gas, krypton-81m gas, and radioactive aerosols. Each offers unique advantages for assessing lung function and regional ventilation.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Role of interleukin-12 in the regulation of CD4+ T cell apoptosis in a mouse model of asthma.

Clinical and experimental immunology·2003
Same author

[A case of Mycobacterium intracellulare infection complicated by immotile cilia syndrome].

Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society·2001
Same author

Heme oxygenase-1 (HO-1) protein induction in a mouse model of asthma.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology·2001
Same author

Fever, cough, and nodules on ankles.

Lancet (London, England)·1999
Same author

[Pleural malignant mesothelioma complicated by multiple myeloma].

Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society·1999
Same author

Chronic drug-induced tubulointerstitial nephritis with renal failure associated with propylthiouracil therapy.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association·1999

Area of Science:

  • Nuclear Medicine
  • Pulmonary Medicine
  • Radiopharmacology

Background:

  • Pulmonary nuclear medicine focuses on ventilation and perfusion imaging.
  • Current ventilation studies utilize xenon-133 (133Xe), krypton-81m (81mKr), or radioaerosols.

Purpose of the Study:

  • To review and compare available methods for pulmonary ventilation studies.
  • To highlight the capabilities and applications of different ventilation imaging tracers.

Main Methods:

  • Xenon-133 (133Xe) gas: single-breath, serial imaging, and washout phases.
  • Krypton-81m (81mKr) gas: utilizes short half-life for dynamic imaging and pre/post-intervention studies.
  • Radioaerosols: deposition by impaction, sedimentation, and random contact for regional ventilation assessment.

Main Results:

  • 133Xe washout is sensitive for detecting slow lung compartments.
  • 81mKr allows for rapid, serial ventilation scans and functional assessments.
  • Radioaerosols provide regional ventilation data through particle deposition.

Conclusions:

  • Advancements in radiopharmaceuticals and imaging techniques, including SPECT, enhance pulmonary nuclear medicine.
  • Each ventilation study method offers distinct benefits for diagnosing and evaluating lung conditions.
  • Nuclear medicine continues to expand its diagnostic capabilities in pulmonary imaging.

Related Experiment Videos