Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Psychiatry

F K Goodwin1

  • 1National Institute of Mental Health, Bethesda, Md.

JAMA
|June 1, 1994
PubMed
Summary
This summary is machine-generated.

Many people seek mental health services annually, often from non-specialists. Childhood behavioral and neuropsychiatric issues may stem from antineuronal antibodies triggered by streptococcal infections.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Corrigendum to: Antidepressants worsen rapid-cycling course in bipolar disorder: A STEP-BD randomized clinical trial. J. Affect. Disord. (Jun. 10, 2015); http://dx.doi.org/10.1016/j.jad.2015.04.054.

Journal of affective disorders·2017
Same author

Prospects for a scientific psychiatry.

Acta neuropsychiatrica·2016
Same author

Bipolar disorder.

Dialogues in clinical neuroscience·2011
Same author

The bipolar spectrum and the antidepressant view of the world.

Journal of psychiatric practice·2005
Same author

What is to be done? Controversies in the diagnosis and treatment of manic-depressive illness.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry·2003
Same author

Topiramate treatment of bipolar spectrum disorders: a retrospective chart review.

Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists·2002
Same journal

WHO Issues Guidelines for Treating Ebola and Marburg Viruses.

JAMA·2026
Same journal

FDA Approves Additional Naloxone Nasal Spray for Opioid Overdose.

JAMA·2026
Same journal

HIV May Hide in More Cells Than Previously Thought-Here's What That Could Mean for a Cure.

JAMA·2026
Same journal

US Dietary Supplement Use Increasing, Especially in Older Adults.

JAMA·2026
Same journal

Heat Stress From Climate Change Surges Globally.

JAMA·2026
Same journal

Strength Training Linked With Lower Cardiovascular Disease Risk in Women.

JAMA·2026
See all related articles

Area of Science:

  • Neuroscience
  • Pediatrics
  • Immunology

Background:

  • 11% of the population utilize mental health services yearly.
  • Most individuals receive care from non-psychiatrist physicians or emergency departments.
  • Childhood behavioral and neuropsychiatric disorders are significant public health concerns.

Purpose of the Study:

  • To explore the potential link between streptococcal infections and childhood neuropsychiatric conditions.
  • To investigate the role of antineuronal antibodies in these disorders.

Main Methods:

  • Review of existing literature on streptococcal infections and neuropsychiatric outcomes.
  • Analysis of potential mechanisms involving antineuronal antibodies.

Main Results:

Related Experiment Videos

  • Group A beta-hemolytic streptococci infections can trigger an immune response.
  • This immune response may involve the production of antineuronal antibodies.
  • These antibodies could mediate behavioral and neuropsychiatric problems in children.

Conclusions:

  • Infections, specifically Group A beta-hemolytic streptococci, may play a role in the etiology of certain childhood neuropsychiatric disorders.
  • Antineuronal antibodies are a potential mechanism linking infection to these conditions.
  • Further research is warranted to confirm this association and explore therapeutic implications.