[Nucleotide sequence of the E1B area and the adjacent 3'-terminal segment of the E1A oncogene from monkey adenovirus...

The SA7 (C8) simian adenovirus was sequenced from the 1478th to 3194th nucleotide. The region includes the 3'-terminal part of E1A and the major part of the E1B coding region. The sequence obtained was compared with the structure of SA7 (P) DNA previously determined in the region 1-2338, and many differences were found which are nucleotide substitutions, microdeletions and microinsertions. Among point substitutions the most frequent was the C-->T transition in CG pairs known as hot spots of mutations. Differences of our sequence from the previously published one was also revealed.