Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Submacular choroidal circulation

J T Ernest, W H Stern, D B Archer

    American Journal of Ophthalmology
    |May 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    This study reveals how blood flows in the eye's choroid. Normally, one arteriole supplies a choriocapillaris lobule, but increased venous pressure can cause blood to flow backward into adjacent lobules.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The role of CRE1 in nucleosome positioning within the cbh1 promoter and coding regions of Trichoderma reesei.

    Applied microbiology and biotechnology·2013
    Same author

    Yeast identification: reassessment of assimilation tests as sole universal identifiers.

    Letters in applied microbiology·2011
    Same author

    SOD1-targeted gene disruption in the ericoid mycorrhizal fungus Oidiodendron maius reduces conidiation and the capacity for mycorrhization.

    Molecular plant-microbe interactions : MPMI·2009
    Same author

    Modulation of chaperone gene expression in mutagenized Saccharomyces cerevisiae strains developed for recombinant human albumin production results in increased production of multiple heterologous proteins.

    Applied and environmental microbiology·2008
    Same author

    Spore germination in Mortierella alpina is associated with a transient depletion of arachidonic acid and induction of fatty acid desaturase gene expression.

    Archives of microbiology·2007
    Same author

    UPR-independent dithiothreitol stress-induced genes in Aspergillus niger.

    Molecular genetics and genomics : MGG·2005
    Same journal

    Reply to Comment on Visual Field Progression in Glaucoma Patients with Delayed Follow-Up.

    American journal of ophthalmology·2026
    Same journal

    Comment on: "Safety and efficiency reducing retinopathy of prematurity guideline sensitivity: an external validation using a large US-based dataset".

    American journal of ophthalmology·2026
    Same journal

    Reply to Comment on "Clinicopathological and Imaging Distinction Between Ocular Adnexal MALT Lymphoma and IgG4-Related Ophthalmic Disease".

    American journal of ophthalmology·2026
    Same journal

    Comment on: Visual Field Progression in Glaucoma Patients With Delayed Follow-Up.

    American journal of ophthalmology·2026
    Same journal

    Corneal sensitivity changes and nerve plexus abnormalities in noninfectious anterior uveitis.

    American journal of ophthalmology·2026
    Same journal

    Role of Menopausal Hormone Therapy on Strabismus, Strabismus Surgery, and Reoperation Rates.

    American journal of ophthalmology·2026
    See all related articles

    Area of Science:

    • Ophthalmology
    • Vascular Biology
    • Anatomy

    Background:

    • The choriocapillaris is a crucial vascular layer in the eye, responsible for nourishing the outer retina.
    • Understanding its unique vascular architecture and flow dynamics is essential for diagnosing and treating various ocular conditions.

    Purpose of the Study:

    • To investigate the microvascular architecture and blood flow patterns within the human choriocapillaris.
    • To elucidate the mechanisms of blood flow regulation and potential retrograde flow under altered venous pressure conditions.

    Main Methods:

    • A neoprene latex and pigment mixture was injected into the choroidal blood vessels of human cadaver eyes.
    • Vascular filling patterns were observed under normal and experimentally elevated venous pressure conditions.

    Related Experiment Videos

    Main Results:

    • Under normal peripheral resistance, a single arteriole exclusively supplied a single lobule of the choriocapillaris.
    • This lobule was drained by multiple surrounding venules.
    • Elevated venous pressure, simulating increased peripheral resistance, induced retrograde filling of contiguous lobules via their normally draining venules, highlighting interconnectedness of choroidal veins.

    Conclusions:

    • The human choriocapillaris exhibits a lobular structure supplied by single arterioles and drained by multiple venules.
    • Choroidal veins are interconnected, allowing for retrograde blood flow into adjacent lobules when venous pressure increases.