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[Lung function reference values for students 6 to 16 years of age]

M Newberger1, M Kundi, W Wiesenberger

  • 1Abt. f. Präventivmedizin, Univ., Wien.

Pneumologie (Stuttgart, Germany)
|March 1, 1994
PubMed
Summary

This study established new lung function reference values for 18,106 Austrian children and adolescents aged 6-16. These updated pediatric reference values enhance early detection of respiratory diseases and dysfunctions.

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Area of Science:

  • Pediatric Pulmonology
  • Environmental Health
  • Biostatistics

Context:

  • Current pediatric lung function reference values in Europe are based on limited, select child populations, potentially biasing assessments.
  • Accurate assessment of lung function and airway growth in children is crucial for diagnosing impairments and evaluating environmental influences.
  • Early detection of small airway disease in children relies on flow-volume measurements, necessitating reliable reference data.

Purpose:

  • To establish updated, robust reference values for lung function parameters in a large cohort of Austrian children and adolescents.
  • To provide a basis for evaluating individual lung function using SD-scores, improving diagnostic accuracy.
  • To address the limitations of existing European reference values derived from small, highly selected groups.

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Summary:

  • A large-scale study involving 18,106 Austrian school children (ages 6-16) established new reference values for lung function parameters including FVC, FEV1, PEF, MEF75, MEF50, MEF25, and MMEF.
  • Regression analysis incorporating standing height, sex, age, and weight was used to predict lung function. Means and SDs for healthy children are presented.
  • Findings indicated higher flow measures for small airway function in adolescent girls, with MEF25 showing the most variability.

Impact:

  • The new reference values offer improved tools for the early identification of respiratory diseases and dysfunctions in pediatric populations.
  • These data will aid in evaluating the impact of environmental and other factors on lung and airway function and growth in children.
  • Provides a more accurate and reliable method for assessing lung health in children and adolescents across diverse settings.