Central effects of thyrotropin-releasing factor (TRF); interaction with some antipsychotic drugs

The behavioral effects (tremors, tail erection, increased motility) of intracerebrally injected TRF are enhanced by pretreatment with chlorpromazine, reserpine and sulpiride; haloperidol does not exert appreciable effects. L-Dopa attenuates or abolishes the potentiation.