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[Herpes zoster treated with acyclovir]

H Grempel1, D Rozenman, F Zuckerman

  • 1Dermatology Dept., Central Emek Hospital, Afula.

Harefuah
|April 1, 1994
PubMed
Summary
This summary is machine-generated.

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This study on herpes zoster patients found cranial nerve involvement common, especially in older adults. Acyclovir treatment showed potential in reducing rash spread and nerve pain.

Area of Science:

  • Virology
  • Dermatology
  • Epidemiology

Context:

  • Herpes zoster (shingles) is a viral infection caused by the varicella-zoster virus.
  • Hospitalized patients provide valuable data on disease presentation and management.
  • Understanding risk factors and treatment efficacy is crucial for patient care.

Purpose:

  • To analyze the clinical characteristics, complications, and treatment outcomes of hospitalized herpes zoster patients.
  • To evaluate the efficacy of acyclovir in managing herpes zoster and its complications.
  • To correlate patient demographics and immune status with disease presentation and severity.

Summary:

  • A 5-year study followed 99 hospitalized herpes zoster patients, analyzing age, sex, rash location, complications, and treatment.

Related Experiment Videos

  • The 6th and 7th decades were most affected; cranial nerve involvement occurred in 35% of cases.
  • Generalized rash was more prevalent in immunocompromised individuals. Acyclovir demonstrated a partial inhibitory effect on rash spread and reduced herpetic neuralgia frequency.

    • Impact:

    • Provides insights into the epidemiology and clinical spectrum of herpes zoster in a hospitalized cohort.
    • Highlights the potential benefits of acyclovir in managing herpes zoster symptoms and preventing complications.
    • Informs clinical practice regarding patient risk stratification and therapeutic interventions for herpes zoster.