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Maculopapular eruption in hypoparathyroidism

M Waisman, S O'Regan

    Archives of Dermatology
    |July 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Idiopathic hypoparathyroidism can cause a distinctive skin rash. This erythematous, maculopapular eruption resolved with normalized serum calcium levels in a pediatric patient.

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    Area of Science:

    • Endocrinology
    • Dermatology
    • Pediatric Medicine

    Background:

    • Idiopathic hypoparathyroidism is a rare endocrine disorder characterized by insufficient parathyroid hormone production.
    • This condition leads to hypocalcemia, a state of low serum calcium levels.
    • Manifestations of hypoparathyroidism can extend beyond metabolic disturbances to include cutaneous findings.

    Observation:

    • A 12-year-old female presented with an erythematous, follicular, maculopapular rash primarily on her trunk and arms.
    • The patient had a documented history of idiopathic hypoparathyroidism.
    • The clinical presentation suggested a potential link between the endocrine disorder and the dermatological symptoms.

    Findings:

    • The observed skin eruption showed a direct correlation with serum calcium levels.

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  • As serum calcium levels normalized, the erythematous, maculopapular rash gradually abated.
  • This finding supports a causal relationship between hypocalcemia and the specific type of skin manifestation.

    • Implications:

    • This case highlights a potential, previously under-recognized cutaneous manifestation of idiopathic hypoparathyroidism.
    • Monitoring for dermatological symptoms may be beneficial in patients with hypoparathyroidism.
    • Understanding this association can aid in earlier diagnosis and management of both endocrine and dermatological aspects.