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Intravenous immunoglobulin, plasmalymphocytapheresis and azathioprine in chronic progressive multiple sclerosis
A Uccelli1, E Capello, D Fenoglio
1Istituto di Clinica Neurologica e C.N.R. Centro per la Neurofisiologia Cerebrale, Università di Genova.
Italian Journal of Neurological Sciences
|February 1, 1994
Abstract:
Five patients with a severe form of chronic progressive multiple sclerosis no longer responsive to steroid therapy were treated for six months with high-dose intravenous immunoglobulin associated with plasmalymphocytapheresis and azathioprine. In spite of an apparent initial stabilization of the course of the disease, EDSS assessment after six and twelve months of therapy revealed progressive disability in all patients.