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Esophageal dysphagia

P J Kahrilas1, G A Ergun

  • 1Department of Medicine, Northwestern University, Chicago, Illinois.

Acta Oto-Rhino-Laryngologica Belgica
|January 1, 1994
PubMed
Summary
This summary is machine-generated.

This review covers esophageal conditions, including strictures, esophagitis in immunocompromised patients, achalasia, spasm, and gastroesophageal reflux disease (GERD). It emphasizes diagnosis, therapy, and the dual sphincter theory for GERD management.

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Area of Science:

  • Gastroenterology
  • Esophageal Physiology
  • Esophageal Pathology

Background:

  • Comprehensive review of esophageal anatomy and physiology.
  • Discussion of various esophageal disorders and their pathophysiology.
  • Focus on current therapeutic strategies and diagnostic approaches.

Purpose of the Study:

  • To provide an overview of esophageal diseases.
  • To detail diagnostic and therapeutic modalities for esophageal strictures, esophagitis, achalasia, spasm, and GERD.
  • To highlight the dual sphincter theory in GERD.

Main Methods:

  • Literature review of esophageal anatomy, physiology, and pathophysiology.
  • Synthesis of information on diagnosis and therapy for benign and malignant esophageal strictures.

Related Experiment Videos

  • Review of esophagitis in immunocompromised hosts (HIV, chemotherapy, transplant recipients).
  • Examination of achalasia and esophageal spasm pathophysiology and treatment.
  • Analysis of current concepts in GERD pathophysiology and therapy.

    • Main Results:

    • Detailed discussion on esophageal dilation and tumor ablation for strictures.
    • Insights into esophagitis management in immunocompromised individuals.
    • Review of treatment options for achalasia and esophageal spasm.
    • Emphasis on the dual sphincter theory for gastroesophageal junction competence.
    • Highlighting the importance of maintenance anti-secretory therapy for GERD.

    Conclusions:

    • Effective management strategies exist for various esophageal conditions.
    • Understanding pathophysiology is crucial for targeted therapy.
    • The dual sphincter theory provides a framework for GERD management.
    • Maintenance anti-secretory therapy is vital for GERD control.