Related Experiment Videos
GFAP-specific oligoclonal bands in the CSF of a patient with acute myelitis
1Department of Neurology, University of Freiburg, Germany.
The specificity for GFAP (glial fibrillary acidic protein) of oligoclonal IgG bands in the CSF of a patient with acute myelitis was demonstrated by isoelectric focusing and affinity blotting. Findings were confirmed by western blotting using a monoclonal antibody to GFAP as a reference. Immune reactions to this astrocyte protein are considered as arising secondary to spinal cord tissue lesion.
The specificity for GFAP (glial fibrillary acidic protein) of oligoclonal IgG bands in the CSF of a patient with acute myelitis was demonstrated by isoelectric focusing and affinity blotting. Findings were confirmed by western blotting using a monoclonal antibody to GFAP as a reference. Immune reactions to this astrocyte protein are considered as arising secondary to spinal cord tissue lesion.