Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Prognostic parameters in benign astrocytomas

L Westergaard1, F Gjerris, L Klinken

  • 1University Clinic of Neurosurgery, Rigshospitalet, Copenhagen, Denmark.

Acta Neurochirurgica
|January 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Thoracic intervertebral disc herniation.

Acta neurologica Scandinavica·2009
Same author

Differential effects of insulin detemir and neutral protamine Hagedorn (NPH) insulin on hepatic glucose production and peripheral glucose uptake during hypoglycaemia in type 1 diabetes.

Diabetologia·2009
Same author

Effects of recombinant LH treatment on folliculogenesis and responsiveness to FSH stimulation.

Human reproduction (Oxford, England)·2007
Same author

Idiopathic normal-pressure hydrocephalus: clinical comorbidity correlated with cerebral biopsy findings and outcome of cerebrospinal fluid shunting.

Journal of neurology, neurosurgery, and psychiatry·2006
Same author

Increasing incidence of childhood tumours of the central nervous system in Denmark, 1980-1996.

British journal of cancer·2006
Same author

What is new about idiopathic intracranial hypertension? An updated review of mechanism and treatment.

Cephalalgia : an international journal of headache·2006
Same journal

De novo contralateral vertebral artery dissection after treatment: incidence and clinical characteristics.

Acta neurochirurgica·2026
Same journal

Comparative analysis of the efficacy and safety of dural sealants in preventing complications after craniotomy: a systematic review and Bayesian network meta-analysis.

Acta neurochirurgica·2026
Same journal

OpenOR - a virtual reality framework for medical education.

Acta neurochirurgica·2026
Same journal

Vascular-based compartmental resection of anterior clinoidal meningiomas: an inter-perforator microdebulking strategy.

Acta neurochirurgica·2026
Same journal

How I do it: microvascular decompression for classical trigeminal neuralgia by arterial compression.

Acta neurochirurgica·2026
Same journal

From antimicrobial-impregnated to standard catheters for external ventricular drainage: a single-center before-and-after cohort study.

Acta neurochirurgica·2026
See all related articles

Pilocytic astrocytomas show an excellent prognosis. Postoperative radiotherapy did not improve survival for non-pilocytic astrocytomas, suggesting further research is needed.

Area of Science:

  • Neuro-oncology
  • Neurosurgery
  • Pathology

Background:

  • Benign astrocytomas represent a heterogeneous group of primary brain tumors.
  • Understanding the prognosis of different subtypes and the role of adjuvant therapies is crucial for patient management.

Purpose of the Study:

  • To determine the prognosis of various benign astrocytoma subtypes.
  • To evaluate the efficacy of postoperative radiotherapy in partially resected benign astrocytomas.

Main Methods:

  • Retrospective analysis of 300 patients diagnosed with benign astrocytomas between 1956 and 1991.
  • Multivariate regression analysis to identify prognostic factors for non-pilocytic supratentorial astrocytomas.

Main Results:

  • Pilocytic astrocytoma demonstrated a significantly better prognosis, warranting classification as a distinct entity.

Related Experiment Videos

  • Age, tumor site, Kernohan grade, and lymphocytic perivascular cuffing were significant prognostic factors for non-pilocytic supratentorial astrocytomas.
  • Postoperative radiotherapy did not show a significant impact on median survival time for non-pilocytic supratentorial benign astrocytomas.

    • Conclusions:

    • Pilocytic astrocytoma is a distinct entity with a favorable prognosis.
    • Further prospective, multicenter studies are essential to definitively assess the role of radiotherapy in benign astrocytomas.