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Published on: August 24, 2016
Fructose and mineral metabolism
1Department of Biochemistry, University of Missouri, Columbia 65211.
Fructose impacts iron, zinc, and copper absorption. While it enhances iron and zinc uptake, it may decrease copper bioavailability in some species, though human studies show minimal effects.
Area of Science:
- Nutritional Science
- Mineral Metabolism
- Dietary Carbohydrates
Background:
- Fructose is a common dietary sugar with known effects on mineral bioavailability.
- The impact of fructose on copper, iron, and zinc absorption requires detailed investigation.
Purpose of the Study:
- To investigate the effects of fructose on the bioavailability of copper, iron, and zinc.
- To compare fructose's impact on mineral absorption across different species.
Main Methods:
- Animal studies (rats, pigs) and human trials were conducted.
- Diets were controlled for carbohydrate content and source (fructose, sucrose, starch).
- Mineral balance and status indicators were measured.
Main Results:
- Fructose forms complexes with iron, promoting its absorption and that of zinc.
- In rats, fructose and sucrose decreased copper bioavailability compared to starch.
- Pigs showed no significant effect of fructose on copper bioavailability.
- In humans, 20% energy from fructose had no effect on copper balance and minimal impact on copper status.
Conclusions:
- Fructose exhibits differential effects on mineral bioavailability depending on the mineral and species studied.
- While fructose may enhance iron and zinc absorption, its effect on copper is species-dependent and less pronounced in humans.
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