[The cerebral vasoconstrictor effects of malondialdehyde]

Malonic dialdehyde has a pronounced central vasoconstrictor effect, though when given in large doses, it causes a profound decrease in systemic blood pressure, however its vasoconstrictor effects are not directly related to fluctuations in systemic blood pressure. The universal antioxidant alpha-tocopherol acetate abolishes and prevents the central vasoconstrictor effects of malonic dialdehyde.