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Severe sepsis following percutaneous or endoscopic procedures for urinary tract stones
N K O'Keeffe1, A J Mortimer, P A Sambrook
1Department of Urology, University Hospital of South Manchester.
Insights
Severe sepsis following urinary tract stone procedures can be fatal, with a 66% mortality rate observed in this study. All affected patients were female, highlighting a need for caution with these interventions.
Area of Science:
- Urology
- Infectious Disease
- Nephrology
Background:
- Percutaneous and endoscopic procedures are common for upper urinary tract stones.
- Severe sepsis is a life-threatening complication associated with invasive procedures.
- Urinary tract stone treatments carry inherent risks that require careful consideration.
Purpose of the Study:
- To report cases of severe sepsis following urinary tract stone procedures.
- To analyze the clinical features and outcomes of severe sepsis in this context.
- To emphasize the importance of early detection and management of sepsis.
Main Methods:
- Retrospective case series analysis.
- Review of nine patients who developed severe sepsis post-procedure.
- Data collection on patient demographics, procedures, and clinical outcomes.
Main Results:
- Nine cases of severe sepsis were identified following procedures for upper urinary tract stones.
- The mortality rate among these patients was 66%.
- All nine patients experiencing severe sepsis were female, an unexplained observation.
Conclusions:
- Severe sepsis following urinary tract stone procedures has a high mortality rate.
- These procedures, particularly as outpatient interventions, should be approached with caution.
- Prompt diagnosis and aggressive treatment are crucial for patient recovery.
Abstract:
Nine cases of severe sepsis following percutaneous or endoscopic procedures for upper urinary tract stones are reported. The mortality rate was 66%. Despite the fact that approximately 700 procedures were carried out in males and females in roughly equal proportions, a striking but inexplicable feature was that all 9 patients in the study group were female. Severe systemic sepsis has a high mortality rate and any procedure that may put patients at risk of this complication should not be undertaken lightly (and certainly not as an out-patient procedure). Recovery is possible with a high index of suspicion, early intervention and intensive treatment.