Related Experiment Videos
[An analysis of the risk factors of child bronchial asthma]
1Hunan Medical University, Changsha.
Insights
Childhood bronchial asthma is a multifactorial disease. Key risk factors include family history, maternal allergies during pregnancy, and the child's early-life allergy or respiratory illness history.
Area of Science:
- Pediatric Pulmonology
- Environmental Health
- Genetics
Context:
- Childhood bronchial asthma is a significant public health concern with complex etiology.
- Identifying specific risk factors is crucial for effective prevention and management strategies.
- Previous research has indicated various contributing factors, but a comprehensive analysis is needed.
Purpose:
- To identify and quantify the risk factors associated with childhood bronchial asthma using a matched case-control study.
- To explore the association between identified risk factors and the age of the first onset of childhood bronchial asthma.
Summary:
- A 1:1 matched case-control study analyzed risk factors for childhood bronchial asthma.
- Significant risk factors identified include family hereditary history (OR=44.44), maternal ingestion of sensitizing foods (OR=22.52) and maternal allergy history (OR=7.11).
- Childhood allergy history (OR=9.27), infant respiratory disease history (OR=7.71), child's personality (OR=8.01), and residential environment (OR=9.08) were also significant predictors. The age of first onset was linked to allergy history, family history, and residential environment, confirming asthma as a multifactorial disease.
Impact:
- Findings provide crucial insights into the multifactorial nature of childhood bronchial asthma.
- This research can inform targeted public health interventions and clinical risk assessments for pediatric asthma.
- Understanding these risk factors can aid in developing personalized prevention and treatment plans for affected children.
Abstract:
We have analyzed the risk factors of child bronchial asthma by a 1:1 matched case-control study. The results showed that the family hereditary history (OR = 44.44); the history of ingesting sensitizing foods (OR = 22.52) and of allergy (OR = 7.11) in maternal pregnancy; the history of allergy in childhood (OR = 9.27) and of respiratory diseases in infancy (OR = 7.71); the personality of child (OR = 8.01), the residential environment (OR = 9.08), and so on were the risk factors of child bronchial asthma. In addition, we have found that the age of the 1st onset of child bronchial asthma was associated with the following risk factors: the history of allergy in childhood and in maternal pregnancy, the family hereditary history and the residential environment, etc. It is confirmed that the child bronchial asthma is a multifactor disease.