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Clustering on the basis of longitudinal data
E D Schneiderman1, S M Willis, C J Kowalski
1Department of Oral and Maxillofacial Surgery, Baylor College of Dentistry, Dallas, TX 75246.
Computers in Biology and Medicine
|September 1, 1993
Summary
A new PC program, ZDIST, calculates distances between polynomial growth curves from longitudinal data. This tool aids in analyzing individual growth patterns and velocities for clustering analysis.
Area of Science:
- Biometrics
- Longitudinal Data Analysis
- Statistical Computing
Background:
- Analyzing longitudinal data requires methods to quantify differences in individual growth trajectories.
- Estimating polynomial growth curves is a common approach in developmental and health sciences.
- Existing methods may lack user-friendly tools for direct comparison of growth curves.
Purpose of the Study:
- To introduce ZDIST, a menu-driven PC program for calculating distances between polynomial growth curves.
- To provide a computational tool for assessing similarities and differences in longitudinal subject growth.
- To facilitate the application of clustering techniques to growth curve data.
Main Methods:
- Development of a menu-driven PC program named ZDIST.
- Computation of distances based on estimated polynomial growth curves.
- Inclusion of options to use growth velocity and acceleration curves for distance estimation.
- Saving distance matrices in ASCII format for compatibility with other software.
Main Results:
- ZDIST provides a straightforward method for computing inter-individual growth curve distances.
- The program allows flexibility by incorporating raw curve data, velocity, and acceleration estimates.
- Generated distance matrices are compatible with standard clustering algorithms like SYSTAT.
Conclusions:
- ZDIST offers a valuable and accessible tool for researchers analyzing longitudinal growth data.
- The program enhances the ability to perform quantitative comparisons and cluster subjects based on growth patterns.
- Availability of ZDIST supports advancements in the statistical analysis of developmental trajectories.