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Updated: Aug 3, 2026
13:47
Laser Capture Microdissection of Highly Pure Trabecular Meshwork from Mouse Eyes for Gene Expression Analysis
Published on: June 3, 2018
[Clinical analysis of steroid glaucoma]
1Department of Ophthalmology, First Teaching Hospital of Henan Medical University, Zhengzhou.
Summary
Steroid-induced glaucoma from topical dexamethasone or prednisolone can mimic chronic open-angle glaucoma. Discontinuing steroids and using glaucoma medication restored normal intraocular pressure (IOP) in patients.
Area of Science:
- Ophthalmology
- Pharmacology
Context:
- Steroid-induced glaucoma is a significant concern with topical corticosteroid use.
- Topical corticosteroids like dexamethasone and prednisolone are commonly prescribed for ocular conditions.
Purpose:
- To analyze cases of steroid-induced glaucoma resulting from topical dexamethasone or prednisolone administration.
- To describe the clinical presentation, management, and outcomes of steroid-induced glaucoma.
Summary:
- Fifteen cases (26 eyes) of steroid-induced glaucoma were identified between 1970-1990.
- Patients averaged 28 years old; most cases presented with chronic open-angle glaucoma-like features.
- Elevated intraocular pressure (IOP) and increased cup-to-disc (C/D) ratios were common findings.
Impact:
- Immediate discontinuation of topical steroids is crucial for managing steroid-induced glaucoma.
- Most patients achieve normalized IOP within months to a year after treatment cessation.
- This study highlights the importance of monitoring IOP in patients using topical corticosteroids.
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