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Culturing Primary Rat Inner Medullary Collecting Duct Cells
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The VIP2 receptor: molecular characterisation of a cDNA encoding a novel receptor for vasoactive intestinal peptide

E M Lutz1, W J Sheward, K M West

  • 1Department of Pharmacology, University of Edinburgh, UK.

FEBS Letters
|November 8, 1993
PubMed

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G-protein Coupled Receptors

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G-protein Coupled Receptors

G-protein coupled receptors are ligand binding receptors that indirectly affect changes in the cell. The actual receptor is a single polypeptide that transverses the cell membrane seven times creating intracellular and extracellular loops. The extracellular loops create a ligand specific pocket which binds to neurotransmitters or hormones. The intracellular loops holds onto the G-protein.
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GPCRs are also called heptahelical, 7TM, or...